The Impact of Implantation Time During Liver Transplantation on Outcome: A Eurotransplant Cohort Study.

ABSTRACT:

Background

The liver graft quickly rewarms during transplantation when the vascular anastomoses are being performed, potentially impacting on outcomes.

Methods

We investigated the relationship between implantation time and outcome in 5223 recipients of deceased-donor livers transplanted in Eurotransplant (2004-2013). Cox regression analyses were corrected for donor, preservation, and recipient variables. Transplant loss represents all-cause graft failure.

Results

Median implantation time was 41 minutes (interquartile range, 34-51). Implantation time independently associated with transplant loss (adjusted hazard ratio, 1.04 for every 10-minute increase; 95% confidence interval, 1.01-1.07; P = 0.007). The magnitude of the implantation time effect was comparable t

SUBMITTER: Jochmans I 

PROVIDER: S-EPMC6089515 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature