Increasing the Resistance of Living Cells against Oxidative Stress by Nonnatural Surfactants as Membrane Guards.

ABSTRACT: The importation of construction principles or even constituents from biology into materials science is a prevailing concept. Vice versa, the cellular level modification of living systems with nonnatural components is much more difficult to achieve. It has been done for analytical purposes, for example, imaging, to learn something about intracellular processes. Cases describing the improvement of a biological function by the integration of a nonnatural (nano)constituent are extremely rare. Because biological membranes contain some kind of a surfactant, for example, phospholipids, our idea is to modify cells with a newly synthesized surfactant. However, this surfactant is intended to possess an additional functionality, which is the reduction of oxidative stress. We report the synthesis of a

SUBMITTER: Kunkel M 

PROVIDER: S-EPMC6091502 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature