Circadian modulation of light-evoked avoidance/attraction behavior in Drosophila.

ABSTRACT: Many insects show strong behavioral responses to short wavelength light. Drosophila melanogaster exhibit Cryptochrome- and Hyperkinetic-dependent blue and ultraviolet (UV) light avoidance responses that vary by time-of-day, suggesting that these key sensory behaviors are circadian regulated. Here we show mutant flies lacking core clock genes exhibit defects in both time-of-day responses and valence of UV light avoidance/attraction behavior. Non-genetic environmental disruption of the circadian clock by constant UV light exposure leads to complete loss of rhythmic UV light avoidance/attraction behavior. Flies with ablated or electrically silenced circadian lateral ventral neurons have attenuated avoidance response to UV light. We conclude that circadian clock proteins and the circadian late

SUBMITTER: Baik LS 

PROVIDER: S-EPMC6091921 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature