Prenatal concentrations of perfluoroalkyl substances and bone health in British girls at age 17.

ABSTRACT: Prenatal exposures to perfluoroalkyl substances (PFAS) have been associated with developmental outcomes in offspring. We found that prenatal concentrations of some PFAS may be associated with reduced bone mass and size in 17-year-old British girls, although it is not clear whether these associations are driven by body size.

Purpose

PFAS are used to make protective coatings on common household products. Prenatal exposures have been associated with developmental outcomes in offspring. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), we investigated the association between prenatal concentrations of PFAS and bone health in girls at 17 years of age and whether body composition can explain any associations.

Methods

We measured concentrations of perfluo

SUBMITTER: Jeddy Z 

PROVIDER: S-EPMC6093196 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature