Continuous nicotine exposure does not affect resurgence of alcohol seeking in rats.

ABSTRACT: Alcohol is the most commonly used drug in the United States and alcohol abuse can lead to alcohol use disorder. Alcohol use disorder is a persistent condition and relapse rates following successful remission are high. Many factors have been associated with relapse for alcohol use disorder, but identification of these factors has not been well translated into preventative utility. One potentially important factor, concurrent nicotine use, has not been well investigated as a causal factor in relapse for alcohol use disorder. Nicotine increases the value of other stimuli in the environment and may increase the value of alcohol. If nicotine increases the value of alcohol, then nicotine use during and after treatment may make relapse more probable. In the current study, we investigated the effe

SUBMITTER: Frye CCJ 

PROVIDER: S-EPMC6093676 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature