Where and When to Cut? Fluorescein Guidance for Brain Stem and Spinal Cord Tumor Surgery-Technical Note.

ABSTRACT: BACKGROUND:Spinal cord and brain stem lesions require a judicious approach with an optimized trajectory due to a clustering of functions on their surfaces. Intraoperative mapping helps locate function. To confidently locate such lesions, neuronavigation alone lacks the desired accuracy and is of limited use in the spinal cord. OBJECTIVE:To evaluate the clinical value of fluoresceins for initial delineation of such critically located lesions. METHODS:We evaluated fluorescein guidance in the surgical resection of lesions with blood-brain barrier disruption demonstrating contrast enhancement in magnet resonance imaging in the spinal cord and in the brain stem in 3 different patients. Two patients harbored a diffuse cervical and thoracic spinal cord lesion, respectively. Another patient suffer

SUBMITTER: Suero Molina E 

PROVIDER: S-EPMC6093771 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature