7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions.

ABSTRACT:

Background

Baló's concentric sclerosis (BCS) is a rare condition characterized by concentrically layered white matter lesions. While its pathogenesis is unknown, hypoxia-induced tissue injury and chemotactic stimuli have been proposed as potential causes of BCS lesion formation. BCS has been suggested to be a variant of multiple sclerosis (MS). Here, we aimed to elucidate similarities and differences between BCS and MS by describing lesion morphology and localization in high-resolution 7 Tesla (7 T) magnetic resonance imaging (MRI) scans.

Methods

Ten patients with Baló-type lesions underwent 7 T MRI, and 10 relapsing remitting MS patients served as controls. The 7 T MR imaging protocol included 3D T₁-weighted (T₁w) magnetization-prepared rapid gradient

SUBMITTER: Behrens JR 

PROVIDER: S-EPMC6093849 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature