Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution.

ABSTRACT: In experimental evolution, laboratory-controlled conditions select for the adaptation of species, which can be monitored in real time. Despite the current popularity of such experiments, nature's most pervasive biological force was long believed to be observable only on time scales that transcend a researcher's life-span, and studying evolution by natural selection was therefore carried out solely by comparative means. Eventually, microorganisms' propensity for fast evolutionary changes proved us wrong, displaying strong evolutionary adaptations over a limited time, nowadays massively exploited in laboratory evolution experiments. Here, we formulate a guide to experimental evolution with microorganisms, explaining experimental design and discussing evolutionary dynamics and outcomes and ho

SUBMITTER: Van den Bergh B 

PROVIDER: S-EPMC6094045 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature