Surgical treatment of children with total colonic aganglionosis: functional and metabolic long-term outcome.

ABSTRACT:

Background

Total colonic aganglionosis (TCA) is a rare variant of Hirschsprung's disease occurring in 3-10% of the cases. Only few studies reported the long-term clinical and metabolic outcomes of patients with TCA. The aim of this study was to evaluate the functional and metabolic long-term outcomes of children undergoing surgical treatment for TCA.

Methods

A 15-year retrospective study was performed. Blood chemistry tests and stool analysis performed at the last follow-up visit were recorded. Height and weight development were assessed using the corresponding percentiles for age. Faecal continence and quality of life were evaluated using a detailed questionnaire.

Results

Eleven patients were included in the study. The median age at surgery was 6 months (range: 3-72 

SUBMITTER: Urla C 

PROVIDER: S-EPMC6094876 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature