Radiation modality use and cardiopulmonary mortality risk in elderly patients with esophageal cancer.

ABSTRACT:

Background

It is currently unclear whether the superior normal organ-sparing effect of intensity-modulated radiotherapy (IMRT) compared with 3-dimensional radiotherapy (3D) has a clinical impact on survival and cardiopulmonary mortality in patients with esophageal cancer (EC).

Methods

The authors identified 2553 patients aged > 65 years from the Surveillance, Epidemiology, and End Results (SEER)-Medicare and Texas Cancer Registry-Medicare databases who had nonmetastatic EC diagnosed between 2002 and 2009 and were treated with either 3D (2240 patients) or IMRT (313 patients) within 6 months of diagnosis. The outcomes of the 2 cohorts were compared using inverse probability of treatment weighting adjustment.

Results

Except for marital status, year of diagnosis, and SEER

SUBMITTER: Lin SH 

PROVIDER: S-EPMC6095128 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature