Aberrant patterns of neural activity when perceiving emotion from biological motion in schizophrenia.

ABSTRACT: Social perceptual deficits in schizophrenia are well established. Recent work suggests that the ability to extract social information from bodily cues is reduced in patients. However, little is known about the neurobiological mechanisms underlying this deficit. In the current study, 20 schizophrenia patients and 16 controls completed two tasks using point-light animations during fMRI: a basic biological motion task and an emotion in biological motion task. The basic biological motion task was used to localize activity in posterior superior temporal sulcus (pSTS), a critical region for biological motion perception. During the emotion in biological motion task, participants viewed brief videos depicting happiness, fear, anger, or neutral emotions and were asked to decide which emotion was po

SUBMITTER: Jimenez AM 

PROVIDER: S-EPMC6095949 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature