Intensive care support and clinical outcomes of patients with Ebola virus disease (EVD) in West Africa.

ABSTRACT:

Purpose

We investigate the impact on outcome of different levels of supportive treatment in Ebola virus disease (EVD). The NGO EMERGENCY delivered care sequentially at two Ebola Treatment Centres (ETC) in Sierra Leone: first at Lakka (fluids, symptomatic, antibiotic, antimalaria treatment, and hospital level medical care), and thereafter in Goderich, adding organ support in the only African ETC with an equipped and staffed intensive care unit (ETC-ICU).

Methods

The primary outcome in this retrospective cohort study was in-ETC mortality. Secondarily, we used multivariable logistic regression to investigate the independent impact of the IC on mortality by comparing patients in two ETCs, adjusting for potential confounders, including the viral load (base-10 logarithm in copies/

SUBMITTER: Langer M 

PROVIDER: S-EPMC6096698 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature