Comparison of strategies for scalable causal discovery of latent variable models from mixed data.

ABSTRACT: Modern technologies allow large, complex biomedical datasets to be collected from patient cohorts. These datasets are comprised of both continuous and categorical data ("Mixed Data"), and essential variables may be unobserved in this data due to the complex nature of biomedical phenomena. Causal inference algorithms can identify important relationships from biomedical data; however, handling the challenges of causal inference over mixed data with unmeasured confounders in a scalable way is still an open problem. Despite recent advances into causal discovery strategies that could potentially handle these challenges; individually, no study currently exists that comprehensively compares these approaches in this setting. In this paper, we present a comparative study that addresses this problem

SUBMITTER: Raghu VK 

PROVIDER: S-EPMC6096780 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature