Serum Renalase Levels in Adolescents with Primary Hypertension.

ABSTRACT: The prevalence of hypertension in pediatric populations continues to rise. Recent studies suggest that renalase plays an important role in blood pressure regulation. The aim of this study was to evaluate serum renalase concentrations in hypertensive children. This study was a prospective cohort analysis of 88 adolescents (40 girls; 48 boys) aged 11-18 years, divided into two groups: HT-38 subjects with primary hypertension; and R (reference group)-50 subjects with normal blood pressure. Serum renalase concentration was measured using a commercial enzyme-linked immunosorbent assay kit. Hypertensive patients had higher serum renalase levels (median 29.8 µg/mL; Q1-Q3: 26.1-35.8) than the reference group (median 26.8; Q1-Q3: 22.96-29.4, p < 0.01). Serum renalase was strongly related to serum u

SUBMITTER: Lemiesz M 

PROVIDER: S-EPMC6096843 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature