The Relationship of Serum Antigen-Specific and Total Immunoglobulin E with Adult Cardiovascular Diseases.

ABSTRACT: Background: The relationship of serum antigen-specific immunoglobulin E (IgE) with cardiovascular diseases (CVDs) remains poorly understood. This study aimed to explore the association of antigen-specific and total IgE with CVDs using data derived from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. Methods and Results: The association of serum total or antigen-specific IgE levels with CVDs was analyzed by survey-weighted logistic regression modeling, adjusted by age, sex, race, education, body mass index, blood pressure, total cholesterol, C-reactive protein, homocysteine, diabetes, smoking, and alcohol consumption. 4953 subjects were included. Coronary heart disease was significantly related to serum total IgE levels. The association of serum total IgE levels wit

SUBMITTER: Xu Z 

PROVIDER: S-EPMC6097256 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature