Drug therapy and other factors associated with the development of acute kidney injury in critically ill patients: a cross-sectional study.

ABSTRACT:

Background

Acute kidney injury (AKI) is associated with a significant increase in morbidity, mortality, and health care costs. In intensive care units (ICU), AKI is commonly multifactorial and frequently involves diverse factors, such as hypovolemia, sepsis, and the use of nephrotoxic drugs. We aimed to investigate drug therapy and other factors associated with the development of AKI in a Brazilian public hospital.

Methods

This is a cross-sectional study involving critically ill patients at an ICU of a tertiary hospital. All data on sequential serum creatinine (S_Cr) level, glomerular filtration rate (GFR), and urine output were collected during ICU stay. The primary outcome was the occurrence of AKI assessed by the Acute Kidney Injury Network (AKIN) criterion. Soc

SUBMITTER: Soares DB 

PROVIDER: S-EPMC6097492 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature