Development of a novel salivary gland cancer lymph node staging system.

ABSTRACT:

Background

Current lymph node (LN) staging for salivary gland cancer (SGC) is extrapolated from mucosal head and neck squamous cell carcinoma. However, given its unique biology and clinical behavior, it is possible that a SGC-specific LN staging system would be more accurate.

Methods

Patients from the National Cancer Data Base with nonmetastatic SGC of the head and neck who were diagnosed from 2004 through 2013 and underwent surgical resection and neck dissection removing at least 10 LNs were included. Multivariable models were constructed to assess the association between survival and LN factors, including number of metastatic LNs, extranodal extension, LN size, and lower LN involvement.

Results

Overall, 4520 patients met the inclusion criteria. An increasing number

SUBMITTER: Aro K 

PROVIDER: S-EPMC6097925 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature