Porous SnO₂ nanoparticles based ion chromatographic determination of non-fluorescent antibiotic (chloramphenicol) in complex samples.

ABSTRACT: Nowadays, there are rising concerns about the extensive use of the antibiotics such as chloramphenicol (CAP), has threatened the human life in the form of various vicious diseases. The limited selectivity and sensitivity of confirmatory techniques (UV and electrochemical) and non-fluorescence property of CAP make its determination a challenging task in the modern pharmaceutical analysis. In order to redeem the selective, sensitive and cost-effective fluorescence methodology, here by the dual role of synthesized porous SnO₂ nanoparticles were exploited; (i) a porous sorbent in a µ-QuEChERS based sample preparation and as (ii) a stimulant for the transformation of non-fluorescent analytes namely CAP and p-nitrophenol (p-NP) into their respective fluorescent product. We report a gr

SUBMITTER: Muhammad N 

PROVIDER: S-EPMC6098012 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature