The correlation of asymmetrical functional connectivity with cognition and reperfusion in carotid stenosis patients.

ABSTRACT:

Objective

Neural disruption and cognitive impairment have been reported in patients with carotid stenosis (CS), but carotid artery stenting (CAS) may not contribute to the cognitive recovery. Although functional hyper-connectivity is one of the physiological over-compensation phenomena in neurological diseases, the literature on the cognitive influence of functional hyper-connectivity in CS patients is limited. We aimed to investigate the longitudinal changes of hyper-connectivity after CAS and its association with cognition in CS patients.

Methods

Thirteen patients with unilateral CS and 17 controls without CS were included. Cognitive function was evaluated at baseline, and resting-state functional MRI was performed 1 week before and 1 month and 1 year after CAS. Comparison

SUBMITTER: Huang KL 

PROVIDER: S-EPMC6098231 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature