Clinical impact of endocapillary proliferation according to the Oxford classification among adults with Henoch-Schonlein purpura nephritis: a multicenter retrospective cohort study.

ABSTRACT:

Background

Henoch-Schönlein purpura nephritis (HSPN) is a form of small vessel vasculitis associated with purpura and IgA deposition in the glomeruli. The International Study of Kidney Disease in Children (ISKDC) classification predicts renal prognosis in children with HSPN, but not in adults. Additionally, it is not well known whether the Oxford classification 2016 and/or the Japanese Histologic classification (JHC) are associated with renal outcome. Herein, we investigated the relationship between pathological characteristics and renal outcome among adult patients with HSPN.

Methods

A multicenter retrospective cohort study was conducted in adult patients with HSPN who underwent renal biopsy between 2004 and 2014. Two nephrologists classified each patient according to the O

SUBMITTER: Inagaki K 

PROVIDER: S-EPMC6098628 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature