Preoperative serum ST2 level predicts acute kidney injury after adult cardiac surgery.

ABSTRACT: OBJECTIVE:The purpose of this study was to evaluate the relationship between preoperative levels of serum soluble ST2 (ST2) and acute kidney injury (AKI) after cardiac surgery. Previous research has shown that biomarkers facilitate the prediction of AKI and other complications after cardiac surgery. METHODS:Preoperative ST2 proteins were measured in 1498 patients undergoing isolated coronary artery bypass graft surgery at 8 hospitals participating in the Northern New England Biomarker Study from 2004 to 2007. AKI severity was defined using the Acute Kidney Injury Network (AKIN) definition. Preoperative ST2 levels were measured using multiplex assays. Ordered logistic regression was used to examine the relationship between ST2 levels and levels of AKI severity. RESULTS:Participants in this

SUBMITTER: Lobdell KW 

PROVIDER: S-EPMC6098731 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature