Conserved Genome Organization and Core Transcriptome of the Lactobacillus acidophilus Complex.

ABSTRACT: The Lactobacillus genus encompasses a genetically and functionally diverse group of species, and contains many strains widely formulated in the human food supply chain as probiotics and starter cultures. Within this genetically expansive group, there are several distinct clades that have high levels of homology, one of which is the Lactobacillus acidophilus group. Of the uniting features, small genomes, low GC content, adaptation to dairy environments, and fastidious growth requirements, are some of the most defining characteristics of this group. To better understand what truly links and defines this clade, we sought to characterize the genomic organization and content of the genomes of several members of this group. Through core genome analysis we explored the synteny and i

SUBMITTER: Crawley AB 

PROVIDER: S-EPMC6099100 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature