Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages.

ABSTRACT: BACKGROUND AND PURPOSE:The deleterious effect of hyperthermia on intracerebral hemorrhage (ICH) has been studied. However, the results are not conclusive and new studies are needed to elucidate clinical factors that influence the poor outcome. The aim of this study was to identify the clinical factors (including ICH etiology) that influence the poor outcome associated with hyperthermia and ICH. We also tried to identify potential mechanisms involved in hyperthermia during ICH. METHODS:We conducted a retrospective study enrolling patients with non-traumatic ICH from a prospective registry. We used logistic regression models to analyze the influence of hyperthermia in relation to different inflammatory and endothelial dysfunction markers, hematoma growth and edema volume in hypertensive and

SUBMITTER: Iglesias-Rey R 

PROVIDER: S-EPMC6099376 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature