Multicentre phase II trial of near-infrared imaging in elective colorectal surgery.

ABSTRACT:

Background

Decreasing anastomotic leak rates remain a major goal in colorectal surgery. Assessing intraoperative perfusion by indocyanine green (ICG) with near-infrared (NIR) visualization may assist in selection of intestinal transection level and subsequent anastomotic vascular sufficiency. This study examined the use of NIR-ICG imaging in colorectal surgery.

Methods

This was a prospective phase II study (NCT02459405) of non-selected patients undergoing any elective colorectal operation with anastomosis over a 3-year interval in three tertiary hospitals. A standard protocol was followed to assess NIR-ICG perfusion before and after anastomosis construction in comparison with standard operator visual assessment alone.

Results

Five hundred and four patients (median age

SUBMITTER: Ris F 

PROVIDER: S-EPMC6099466 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature