Rapid Characterization of Components in Bolbostemma paniculatum by UPLC/LTQ-Orbitrap MSⁿ Analysis and Multivariate Statistical Analysis for Herb Discrimination.

ABSTRACT: Bolbostemma paniculatum is a traditional Chinese medicine (TCM) showed various therapeutic effects. Owing to its complex chemical composition, few investigations have acquired a comprehensive cognition for the chemical profiles of this herb and explicated the differences between samples collected from different places. In this study, a strategy based on UPLC tandem LTQ-Orbitrap MSⁿ was established for characterizing chemical components of B. paniculatum. Through a systematic identification strategy, a total of 60 components in B. paniculatum were rapidly separated in 30 min and identified. Then based on peak intensities of all the characterized components, principle component analysis (PCA) and hierarchical cluster analysis (HCA) were employed to classify 18

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC6100040 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature