Dual cobalt-copper light-driven catalytic reduction of aldehydes and aromatic ketones in aqueous media.

ABSTRACT: We present an efficient, general, fast, and robust light-driven methodology based on earth-abundant elements to reduce aryl ketones, and both aryl and aliphatic aldehydes (up to 1400 TON). The catalytic system consists of a robust and well-defined aminopyridyl cobalt complex active for photocatalytic water reduction and the [Cu(bathocuproine)(Xantphos)](PF₆) photoredox catalyst. The dual cobalt-copper system uses visible light as the driving-force and H₂O and an electron donor (Et₃N or ⁱPr₂EtN) as the hydride source. The catalytic system operates in aqueous mixtures (80-60% water) with high selectivity towards the reduction of organic substrates (>2000) vs. water reduction, and tolerates O₂. High selectivity towards t

SUBMITTER: Call A 

PROVIDER: S-EPMC6100254 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature