Reconstruction of real and simulated phylogenies based on quartet plurality inference.

ABSTRACT:

Background

Deciphering the history of life on Earth has long been regarded as one of the most central tasks in biology. In past years, widespread discordance between the evolutionary histories of different groups of orthologous genes of prokaryotes have been revealed, primarily due to horizontal gene transfers (HGTs). Nonetheless, evidence that support a strong tree-like signal of evolution have been uncovered, despite the presence of HGT events. Therefore, a challenging task is to distill this tree-like signal from the noise induced by all sources of non-tree-like events.

Results

In this work we tackle this question, using real and simulated data. We first tighten a recent related theoretical result in this field. In a simulation study, we infer individual quartet topologie

SUBMITTER: Avni E 

PROVIDER: S-EPMC6101080 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature