Visualization of Microbiota in Tick Guts by Whole-mount In Situ Hybridization.

ABSTRACT: Infectious diseases transmitted by arthropod vectors continue to pose a significant threat to human health worldwide. The pathogens causing these diseases, do not exist in isolation when they colonize the vector; rather, they likely engage in interactions with resident microorganisms in the gut lumen. The vector microbiota has been demonstrated to play an important role in pathogen transmission for several vector-borne diseases. Whether resident bacteria in the gut of the Ixodes scapularis tick, the vector of several human pathogens including Borrelia burgdorferi, influence tick transmission of pathogens is not determined. We require methods for characterizing the composition of the bacteria associated with the tick gut to facilitate a better understanding of potential interspecies interac

SUBMITTER: Moss CE 

PROVIDER: S-EPMC6101453 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature