Local Control After Stereotactic Body Radiation Therapy for Liver Tumors.

ABSTRACT:

Purpose

To quantitatively evaluate published experiences with hepatic stereotactic body radiation therapy (SBRT), to determine local control rates after treatment of primary and metastatic liver tumors and to examine whether outcomes are affected by SBRT dosing regimen.

Methods and materials

We identified published articles that reported local control rates after SBRT for primary or metastatic liver tumors. Biologically effective doses (BEDs) were calculated for each dosing regimen using the linear-quadratic equation. We excluded series in which a wide range of BEDs was used. Individual lesion data for local control were extracted from actuarial survival curves, and data were aggregated to form a single dataset. Actuarial local control curves were generated using the Kaplan-

SUBMITTER: Ohri N 

PROVIDER: S-EPMC6102100 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature