Genome-Wide Characterization of Selection Signatures and Runs of Homozygosity in Ugandan Goat Breeds.

ABSTRACT: Both natural and artificial selection are among the main driving forces shaping genetic variation across the genome of livestock species. Selection typically leaves signatures in the genome, which are often characterized by high genetic differentiation across breeds and/or a strong reduction in genetic diversity in regions associated with traits under intense selection pressure. In this study, we evaluated selection signatures and genomic inbreeding coefficients, F_ROH, based on runs of homozygosity (ROH), in six Ugandan goat breeds: Boer (n = 13), and the indigenous breeds Karamojong (n = 15), Kigezi (n = 29), Mubende (n = 29), Small East African (n = 29), and Sebei (n = 29). After genotyping quality control, 45,294 autosomal sing

SUBMITTER: Onzima RB 

PROVIDER: S-EPMC6102322 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature