Self-Reported Effectiveness and Safety of Trokie^® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts.

ABSTRACT: Therapeutic use of cannabinoids, the main active ingredients of Cannabissativa L., is often hindered by their limited bioavailability and undesirable psychoactivity. We conducted an observational study in December 2016 and another one in February 2018 to investigate respectively: (i) the effectiveness of Trokie^® lozenges, a standardized formulation containing cannabis extracts, to deliver cannabinoids via buccal absorption and (ii) its long-term safety. Participants were members of the Palliative Care Corporation health clinic, registered California cannabis patients, and had a diagnosis of chronic non-cancer pain. For the effectiveness study, 49 participants were asked to self-report pain perception before and after 1-12 weeks of taking Trokie^® lozenges

SUBMITTER: Crowley K 

PROVIDER: S-EPMC6102350 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature