Transcriptome analysis of PCOS arrested 2-cell embryos.
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ABSTRACT:
SUBMITTER: Lu C
PROVIDER: S-EPMC6103702 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Transcriptome analysis of PCOS arrested 2-cell embryos.
Lu Cuiling C Chi Hongbin H Wang Yapeng Y Feng Xue X Wang Lina L Huang Shuo S Yan Liying L Lin Shengli S Liu Ping P Qiao Jie J
Cell cycle (Georgetown, Tex.) 20180703 8
In an attempt to explore the early developmental arrest in embryos from polycystic ovarian syndrome (PCOS) patients, we sequenced the transcriptome profiles of PCOS arrested 2-cell embryos, non-PCOS arrested 2-cell embryos and non-arrested 2-cell embryos using single-cell RNA-Seq technique. Differential expression analysis was performed using the DEGSeq R package. Gene Ontology (GO) enrichment was analyzed using the GOseq R package. Data revealed 62 differentially expressed genes between non-PCO ...[more]
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2007-01-22 | GSE5712 | GEO