Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation.

ABSTRACT:

Introduction

Our objectives are to (1) describe the pathogens, site, timing and risk factors for acquired infection during neonatal and pediatric ECMO and (2) explore the association between acquired infection and mortality.

Methods

Secondary analysis of prospective data collected by the Collaborative Pediatric Critical Care Research Network between December 2012 and September 2014. Clinical factors associated with acquired infection were assessed with multivariable Cox regression. Factors associated with mortality were assessed with logistic regression.

Results

Of 481 patients, 247 (51.3%) were neonates and 400 (83.2%) received venoarterial ECMO. Eighty (16.6%) patients acquired one or more infections during ECMO; 60 (12.5%) patients had bacterial, 21 (4.4%) had fung

SUBMITTER: Cashen K 

PROVIDER: S-EPMC6103806 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature