Association between prenatal psychological stress and oxidative stress during pregnancy.

ABSTRACT:

Background

Prenatal psychological stress during pregnancy has been associated with adverse reproductive outcomes. A growing animal literature supports an association between psychological stress and oxidative stress. We assessed this relationship in pregnant women, hypothesising that psychological stress is associated with higher concentrations of oxidative stress biomarkers during pregnancy.

Methods

Psychosocial status and stressful life events (SLE) were self-reported. 8-iso-prostaglandin F_2α (8-iso-PGF_2α ) was measured as a biomarker of oxidative stress in urine samples at median 32 weeks' gestation. We examined SLEs individually (ever vs never) and in summary (any vs none) and psychosocial status as measured by individual subscales and in summary (p

SUBMITTER: Eick SM 

PROVIDER: S-EPMC6103836 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature