The Potential Clinical and Economic Value of Primary Tumour Identification in Metastatic Cancer of Unknown Primary Tumour: A Population-Based Retrospective Matched Cohort Study.

ABSTRACT:

Purpose

Several genomic tests have recently been developed to identify the primary tumour in cancer of unknown primary tumour (CUP). However, the value of identifying the primary tumour in clinical practice for CUP patients remains questionable and difficult to prove in randomized trials.

Objective

We aimed to assess the clinical and economic value of primary tumour identification in CUP using a retrospective matched cohort study.

Methods

We used the Manitoba Cancer Registry to identify all patients initially diagnosed with metastatic cancer between 2002 and 2011. We defined patients as having CUP if their primary tumour was found 6 months or more after initial diagnosis or never found during the course of disease. Otherwise, we considered patients to have metastatic

SUBMITTER: Hannouf MB 

PROVIDER: S-EPMC6103931 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature