Prostate irradiation with focal dose escalation to the intraprostatic dominant nodule: a systematic review.

ABSTRACT: Radiation therapy (RT) is a curative treatment option for localized prostate cancer. Prostate irradiation with focal dose escalation to the intraprostatic dominant nodule (IDN) is an emerging treatment option that involves the prophylactic irradiation of the whole prostate while increasing RT doses to the visible prostatic tumor. Because of the lack of large multicentre trials, a systematic review was performed in an attempt to get an overview on the feasibility and efficacy of focal dose escalation to the IDN. A bibliographic search for articles in English, which were listed in MEDLINE from 2000 to 2016 to identify publications on RT with focal directed boost to the IDN, was performed. The review was completed following the Preferred Reporting Items for Systematic Reviews and Meta-analyse

SUBMITTER: Feutren T 

PROVIDER: S-EPMC6104294 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature