Triplet Excited Carbonyls and Singlet Oxygen Formation During Oxidative Radical Reaction in Skin.

ABSTRACT: The skin is the largest organ in the body and is consistently exposed to aggressive environmental attacks (biological/physical/chemical, etc.). Reactive oxygen species (ROS) are formed during the normal oxidative metabolism which enhances to a lethal level under stress conditions referred to as oxidative stress. While, under normal conditions, cells are capable of dealing with ROS using non-enzymatic and enzymatic defense system, it can lead to a critical damage to cell system via the oxidation of cellular components under stress condition. Lipid peroxidation is a well-established mechanism of cellular injury in all kinds of organisms and it is often used as an indicator of oxidative stress in cells and tissues. In the presence of metal ions, ROS such as hydrogen peroxide (H₂O

SUBMITTER: Prasad A 

PROVIDER: S-EPMC6104306 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature