Predictors of early progression of surgically treated atypical meningiomas.

ABSTRACT:

Background

Clinical behaviour of atypical meningiomas is not uniform. While, as a group, they exhibit a high recurrence rate, some pursue a more benign course, whereas others progress early. We aim to investigate the imaging and pathological factors that predict risk of early tumour progression and to determine whether early progression is related to outcome.

Methods

Adult patients with WHO grade II meningioma treated in three regional referral centres between 2007 and 2014 were included. MRI and pathology characteristics were assessed. Gross total resection (GTR) was defined as Simpson 1-3. Recurrence was classified into early and late (≤ 24 vs. > 24 months).

Results

Among the 220 cases, 37 (16.8%) patients progressed within 24 months of operation. Independent predic

SUBMITTER: Budohoski KP 

PROVIDER: S-EPMC6105233 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature