Identifying auditory cortex encoding abnormalities in schizophrenia: The utility of low-frequency versus 40 Hz steady-state measures.

ABSTRACT: Magnetoencephalography (MEG) and EEG have identified poststimulus low frequency and 40 Hz steady-state auditory encoding abnormalities in schizophrenia (SZ). Negative findings have also appeared. To identify factors contributing to these inconsistencies, healthy control (HC) and SZ group differences were examined in MEG and EEG source space and EEG sensor space, with better group differentiation hypothesized for source than sensor measures given greater predictive utility for source measures. Fifty-five HC and 41 chronic SZ were presented 500 Hz sinusoidal stimuli modulated at 40 Hz during simultaneous whole-head MEG and EEG. MEG and EEG source models using left and right superior temporal gyrus (STG) dipoles estimated trial-to-trial phase similarity and percent change from prestimulus bas

SUBMITTER: Edgar JC 

PROVIDER: S-EPMC6105408 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature