Identification and Characterization of Conjugative Plasmids That Encode Ciprofloxacin Resistance in Salmonella.

ABSTRACT: This study aimed to characterize novel conjugative plasmids that encode transferable ciprofloxacin resistance in Salmonella In this study, 157 nonduplicated Salmonella isolates were recovered from food products, of which 55 were found to be resistant to ciprofloxacin. Interestingly, 37 of the 55 Cip^rSalmonella isolates (67%) did not harbor any mutations in the quinolone resistance-determining regions (QRDR). Six Salmonella isolates were shown to carry two novel types of conjugative plasmids that could transfer the ciprofloxacin resistance phenotype to Escherichia coli J53 (azithromycin resistant [Azi^r]). The first type of conjugative plasmid belonged to the ∼110-kb IncFIB-type conjugative plasmids carrying qnrB-bearing and

SUBMITTER: Chen K 

PROVIDER: S-EPMC6105805 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature