A prospective in silico analysis of interdisciplinary and interobserver spatial variability in post-operative target delineation of high-risk oral cavity cancers: Does physician specialty matter?

ABSTRACT:

Background

The aim of this study was to determine the interdisciplinary agreement in identifying the post-operative tumor bed.

Methods

Three radiation oncologists (ROs), four surgeons, and three radiologists segmented post-operative tumor and nodal beds for three patients with oral cavity cancer. Specialty cohort composite contours were created by STAPLE algorithm implementation results for interspecialty comparison. Dice similarity coefficient and Hausdorff distance were utilized to compare spatial differentials between specialties.

Results

There were significant differences between disciplines in target delineation. There was unacceptable variation in Dice similarity coefficient for each observer and discipline when compared to the STAPLE contours. Within surgery an

SUBMITTER: Ng SP 

PROVIDER: S-EPMC6105928 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature