Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper.

ABSTRACT: Renal perfusion provides the driving pressure for glomerular filtration and delivers the oxygen and nutrients to fuel solute reabsorption. Renal ischaemia is a major mechanism in acute kidney injury and may promote the progression of chronic kidney disease. Thus, quantifying renal tissue perfusion is critically important for both clinicians and physiologists. Current reference techniques for assessing renal tissue perfusion have significant limitations. Arterial spin labelling (ASL) is a magnetic resonance imaging (MRI) technique that uses magnetic labelling of water in arterial blood as an endogenous tracer to generate maps of absolute regional perfusion without requiring exogenous contrast. The technique holds enormous potential for clinical use but remains restricted to research setting

SUBMITTER: Odudu A 

PROVIDER: S-EPMC6106644 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature