Time-domain THz spectroscopy of the characteristics of hydroxyapatite provides a signature of heating in bone tissue.

ABSTRACT: Because of the importance of bone in the biomedical, forensic and archaeological contexts, new investigation techniques are constantly required to better characterize bone ultrastructure. In the present paper, we provide an extended investigation of the vibrational features of bone tissue in the 0.1-3 THz frequency range by time-domain THz spectroscopy. Their assignment is supported by a combination of X-ray diffraction and DFT-normal modes calculations. We investigate the effect of heating on bone tissue and synthetic calcium-phosphates compounds with close structure and composition to bone mineral, including stoichiometric and non-stoichiometric hydroxyapatite (HA), tricalcium phosphate, calcium pyrophosphate and tetracalcium phosphate. We thus demonstrate that the narrow vibrational mod

SUBMITTER: Plazanet M 

PROVIDER: S-EPMC6107136 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature