Total and cause-specific standardized mortality ratios in patients with schizophrenia and/or substance use disorder.

ABSTRACT: Individuals with schizophrenia or substance use disorder have a substantially increased mortality compared to the general population. Despite a high and probably increasing prevalence of comorbid substance use disorder in people with schizophrenia, the mortality in the comorbid group has been less studied and with contrasting results. We performed a nationwide open cohort study from 2009 to 2015, including all Norwegians aged 20-79 with schizophrenia and/or substance use disorder registered in any specialized health care setting in Norway, a total of 125,744 individuals. There were 12,318 deaths in the cohort, and total, sex-, age- and cause-specific standardized mortality ratios (SMRs) were calculated, comparing the number of deaths in patients with schizophrenia, schizophrenia only, subs

SUBMITTER: Heiberg IH 

PROVIDER: S-EPMC6107156 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature