The mode of interfragmentary movement affects bone formation and revascularization after callus distraction.

ABSTRACT: Callus distraction is sometimes associated with a delay in the maturation process and serious complications. It is believed that these complications are often caused by instability of the bone segment fixation. Typical fixation devices, such as ring-fixators, show significant deformations in all directions under external loading and muscle forces. This leads to axial compression and tension as well as shear movements in the healing area. Herein we investigated the hypothesis that the direction of interfragmentary movement after callus distraction affects the bone formation and revascularization during the maturation process. Two custom fixator systems were designed to apply a protocol of lateral callus distraction and subsequent cyclic stimulation of the regenerate tissue. One fixator syst

SUBMITTER: Claes L 

PROVIDER: S-EPMC6107229 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature