AutoVOI: real-time automatic prescription of volume-of-interest for single voxel spectroscopy.

ABSTRACT:

Purpose

To develop a fast and automated volume-of-interest (VOI) prescription pipeline (AutoVOI) for single-voxel MRS that removes the need for manual VOI placement, allows flexible VOI planning in any brain region, and enables high inter- and intra-subject consistency of VOI prescription.

Methods

AutoVOI was designed to transfer pre-defined VOIs from an atlas to the 3D anatomical data of the subject during the scan. The AutoVOI pipeline was optimized for consistency in VOI placement (precision), enhanced coverage of the targeted tissue (accuracy), and fast computation speed. The tool was evaluated against manual VOI placement using existing T₁ -weighted data sets and corresponding VOI prescriptions. Finally, it was implemented on 2 scanner platforms to acquire MR

SUBMITTER: Park YW 

PROVIDER: S-EPMC6107418 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature