Motion-robust sub-millimeter isotropic diffusion imaging through motion corrected generalized slice dithered enhanced resolution (MC-gSlider) acquisition.

ABSTRACT:

Purpose

To develop an efficient MR technique for ultra-high resolution diffusion MRI (dMRI) in the presence of motion.

Methods

gSlider is an SNR-efficient high-resolution dMRI acquisition technique. However, subject motion is inevitable during a prolonged scan for high spatial resolution, leading to potential image artifacts and blurring. In this study, an integrated technique termed Motion Corrected gSlider (MC-gSlider) is proposed to obtain high-quality, high-resolution dMRI in the presence of large in-plane and through-plane motion. A motion-aware reconstruction with spatially adaptive regularization is developed to optimize the conditioning of the image reconstruction under difficult through-plane motion cases. In addition, an approach for intra-volume motion estimation

SUBMITTER: Wang F 

PROVIDER: S-EPMC6107445 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature