Preliminary study on the inhibitory effect of seaweed Gracilaria verrucosa extract on biofilm formation of Candida albicans cultured from the saliva of a smoker.

ABSTRACT: Background:Candida albicans is an opportunistic fungus that might infect the oral cavity. Increased colony numbers of C. albicans in the mouth can be caused by multiple factors, such as smoking, weakened immune system, antibiotics use and immune-compromised condition. Smoking can increase expression of virulence factors of C. albicans and make it stronger. One virulence factor of C. albicans is biofilm formation. The ability of creating biofilm makes C. albicans more tolerant to commercial antifungal agents. The objective of this preliminary study was to examine the ability of the seaweed G.verrucosa extracts to inhibit the formation of biofilm by C. albicans isolated from the saliva of a smoker. Methods: The extract of

SUBMITTER: Mubarak Z 

PROVIDER: S-EPMC6107980 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature