A systematic review comparing the evidence for kidney function outcomes between oral antidiabetic drugs for type 2 diabetes.

ABSTRACT: Background: The development of kidney disease is a serious complication among people with type 2 diabetes mellitus, associated with substantially increased morbidity and mortality.  We aimed to summarise the current evidence for the relationship between treatments for type 2 diabetes and long-term kidney outcomes, by conducting a systematic search and review of relevant studies. Methods: We searched Medline, Embase and Web of Science, between 1st January 1980 and 15th May 2018 for published clinical trials and observational studies comparing two or more classes of oral therapy for type 2 diabetes. We included people receiving oral antidiabetic drugs. Studies were eligible that; (i) compared two or more classes of oral therapy for type 2 diabetes; (ii) reported kidney outcomes

SUBMITTER: Wilkinson SV 

PROVIDER: S-EPMC6107985 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature