Mercury Exposure, Blood Pressure, and Hypertension: A Systematic Review and Dose-response Meta-analysis.

ABSTRACT:

Background

Body burden of mercury has been linked to hypertension in populations exposed to high mercury levels.

Objectives

We summarized, extracted, and pooled the results of published studies that investigated mercury biomarkers and hypertension or blood pressure (BP) measurements to examine this potential relationship.

Methods

We searched PubMed, Embase, and TOXLINE and selected studies according to a priori defined inclusion criteria. Study quality was assessed by the Newcastle-Ottawa scale for cohort and case-control studies and the Quality Assessment Tool for cross-sectional studies. Study estimates were pooled using inverse-variance weighted random-effects models. Dose-response meta-analysis was performed with studies reporting hypertension and systolic

SUBMITTER: Hu XF 

PROVIDER: S-EPMC6108832 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature